Southern Utah University

Course Syllabus

Southern Utah University
Southern Utah University
Fall Semester 2026

ST: Medicinal Chemistry (Face-to-Face)

CHEM 4540-01

Course: CHEM 4540-01
Credits: 3
Term: Fall Semester 2026
Department: Chemistry and Physics
CRN: 31226

Course Description

Explores advanced, modern, and current topics in chemistry. The specific topic will appear on the students’ transcript. This course may be repeated with different topics, but a specific topic cannot be counted more than once for upper-division credit. A minimum grade of “C” (2.0 or above) must be earned in this course before it can be counted in a physical science major or minor or as a prerequisite for any other course. (Fall) [Graded (Standard Letter)]

This upper-division course explores the chemical principles underlying drug design, development, and action. Emphasizing the relationship between molecular structure and biological activity, students will study the synthesis, mechanism of action, and pharmacokinetics of therapeutic agents. Topics include receptor theory, enzyme inhibition, and drug metabolism, with a focus on current strategies in medicinal chemistry.

Required Texts

Required:An Introduction to Medicinal Chemistry” 7th Edition (Patrick) ISBN: 978-0-19-886666-4 or eBook 978-0198866664

Learning Outcomes

There is no way to escape chemistry. One might be able to feign ignorance, but you will never be able to claim that chemistry has no value to your life; chemistry is vital for your daily existence. You may never study chemistry again, and if so, ideally the lessons that will remain with you from this course will be those that helped you achieve the mission of SUU. Specifically, this course will introduce you to the basic principles of chemistry, including these objectives:

  • Develop and apply critical thinking skills in solving problems related to medicinal chemistry.
    (ELO: Inquiry, Critical Thinking, Quantitative Literacy, Problem Solving)
  • Understand the fundamental principles and theories behind the field of medicinal chemistry.
    (ELO: Critical Thinking, Quantitative Literacy)
  • Think critically and analyze physical phenomena using fundamental chemical principles.
    (ELO: Creative Thinking, Critical Thinking)
  • Appreciate chemistry’s benefit to humanity through medicine and quality of life.
    (ELO: Lifelong Learning, Information Literacy)
  • Understand and use chemical vocabulary in the correct context.
    (ELO: Communication, Quantitative Literacy)
  • Understand and describe atoms and molecules in detail, including structure, properties, and reactivity.
    (ELO: Creative Thinking, Communication, Quantitative Literacy)
  • Understand the properties of molecules and biological interactions responsible for drug effects.
    (ELO: Creative Thinking, Critical Thinking, Problem Solving)
  • Understand the implications of a molecule’s structure on its reactivity and potential as a drug.
    (ELO: Creative Thinking, Critical Thinking, Problem Solving)
  • Use chemical principles in predicting drug efficacy, pharmacokinetics, and pharmacodynamics.
    (ELO: Creative Thinking, Critical Thinking, Problem Solving)
  • Use the discussed concepts and principles to understand modern and novel medicinal chemistry problems.
    (ELO: Creative Thinking, Critical Thinking, Problem Solving)

Course Requirements

Distribution of Course Points

Points may be earned through…

Exams3 @ 100% pts300% pts
Application problems(Multiple)100% pts
Student Presentation100% pts
Total points500% pts

To determine % points for an assignment: (Achieved points) / (Points possible) 100 = % pts

The instructor’s goal is to complete the grading of assignments and exams within 1-week from when they were turned in. Scores are posted using Canvas (). Ensure the assignment/assessment score recorded is the one earned. Inform me of any discrepancies.

Assessment Policy

Grades are assigned based on the comparison of the percentage of points earned to the total number possible.

Note: If you are not performing at the level you desire, seek help early to maximize performance on assignments. Do Not ask how to get ‘extra’ points, or for grade bumps, even if you are ‘so close’. This is an especially egregious action in the last couple of weeks of a semester. Final grade curving may occur but doing so after a student’s request raises issues of ethical misconduct. Individuals are not provided opportunities for credit the entire class does not have. These situations lead to loss of employment.

I WILL NOT do that for you! BUT: I will do everything I can, ethically, to assist you in achieving your academic goals.

Exam Dates and Format

Exams consist of multiple choice and short answer problems similar to those in the textbook. Exams cover all material discussed to that point, focusing on the information presented since the last exam. As per department policy, exams will not be returned to students but may be reviewed in-class, during office hours, and by appointment.

Tentative exam dates are as follows: NOTE: Exams cannot be administered after being given to the class!

Homework

You are assigned all the problems at the end of each chapter. These will be collected at the first of class on the date shown on the Reading and Exam Schedule Outline (last page). These "homework" assignments will be graded and the percentage points will be added to count as one exam.

Application Problems

It may be necessary to give extra assignments to illustrate difficult material. In-class or take-home problem sets my be distributed throughout the semester. Prepare for these by reviewing previous lectures and reading for the upcoming lecture. Missed in-class problems cannot be made up/completed under any circumstances. These assignments will also be graded and the percentage points will be added to count as one exam (which includes the chapter questions).

Student Presentation

The student presentation project is an opportunity to dive deeply into topics discussed in the course concerning a certain class of drugs. The three key components considered in grading are the demonstration of thought, evidence of creativity, and illustration of effort. The student presentation is described in a detailed separate handout.

Grading Scale
A100 – 93%B+89. – 87%C+79. – 77%D+69. – 67%
A–92. – 90%B86. – 83%C76. – 73%D66. – 63%
B–82. – 80%C–72. – 70%D–62. – 60%F<60%

Course Outline

Exam Dates
Exam 1Thr, Sep 26Exam 2Thr, Oct 24Exam 3Tue, Nov 21
Reading and Exam Schedule Outline
WKDATETOPICPAGES*NOTES
Sep 3Need to Know Biochemistry
Chapter 1-Drugs and Drug Targets: An Overview
1–14
Sep 10Chapter 2-Protein Structure and Function
Chapter 3-Enzymes: Structure and Function
15–41Chapter 1 HW DUE
Sep 17Chapter 4-Receptors: Structure and Function
Chapter 5-Receptors and Signal Transduction
42–72Chapter 2,3 HW DUE
Sep 24Chapter 6-Nucleic Acids: Structure and Function
Case Studies-
73–85Chapter 4,5 HW DUE
Oct 1Exam 1: Chapters 1–6Chapter 6 HW DUE
Oct 8Chapter 7-Enzymes as Drug Targets
Chapter 8-Receptors as Drug Targets
87–119
Oct 15Chapter 9-Nucleic Acids as Drug Targets
Chapter 10-Miscellaneous Drug Targets
120–151Chapter 7,8 HW DUE
Oct 22Chapter 11-Pharmacokinetics and Related Topics
Case Studies-
152–181Chapter 9,10 HW DUE
Oct 29Exam 2: Chapters 7–11Chapter 11 HW DUE
Nov 5Chapter 12-Drug Discovery: Finding a Lead
Chapter 13-Drug Design: Optimizing Target Interactions
185–240
Nov 12Chapter 14-Drug Design: Optimizing Access to the Target
Chapter 15-Getting the Drug to Market
241–280Chapter 12, 13 HW DUE
Nov 19Case Studies281–304Chapter 14,15 HW DUE
Nov 26Exam 3: Chapters 12–15Case Study DUE
Dec 3–––––––––Thanksgiving Holiday—No Class–––––––––
Dec 10Selected Topics in Medicinal Chemistry-Student Presentations
Dec 17Selected Topics in Medicinal Chemistry-Student PresentationsFinal 11:00 a.m. - 12:50 p.m.
WKDATETOPICPAGES*NOTES
Aug 29Need to Know Biochemistry
Chapter 1-Drugs and Drug Targets: An Overview
1–14
Sep 5Chapter 2-Protein Structure and Function
Chapter 3-Enzymes: Structure and Function
15–41Chapter 1 HW DUE
Sep 12Chapter 4-Receptors: Structure and Function
Chapter 5-Receptors and Signal Transduction
42–72Chapter 2,3 HW DUE
Sep 19Chapter 6-Nucleic Acids: Structure and Function
Case Studies-
73–85Chapter 4,5 HW DUE
Sep 26Exam 1: Chapters 1–6Chapter 6 HW DUE
Oct 3Chapter 7-Enzymes as Drug Targets
Chapter 8-Receptors as Drug Targets
87–119
Oct 10Chapter 8-Receptors as Drug Targets
Chapter 9-Nucleic Acids as Drug Targets
Chapter 7,8 HW DUE
Oct 17Chapter 10-Miscellaneous Drug Targets
Individual Project Discussion
Class Start at 10 am
Chapter 9 HW DUE
Oct 24Chapter 11-Pharmacokinetics and Related Topics
Case Studies-
152–181Chapter 10 HW DUE
Oct 31Exam 2: Chapters 7–11Chapter 11 HW DUE
Nov 7Chapter 12-Drug Discovery: Finding a Lead
Chapter 13-Drug Design: Optimizing Target Interactions
185–240Chapter 12, 13 HW DUE
Nov 14Chapter 14-Drug Design: Optimizing Access to the Target
Chapter 15-Getting the Drug to Market
241–280Chapter 14,15 HW DUE
Nov 21Exam 3: Chapters 12–15
Nov 28–––––––––Thanksgiving Holiday—No Class–––––––––
Dec 5Selected Topics in Medicinal Chemistry-Student Presentations
Dec 11 (Wed)Selected Topics in Medicinal Chemistry-Student Presentations
WKDATETOPICPAGES*NOTES
Aug 29Need to Know Biochemistry
Chapter 1-Drugs and Drug Targets: An Overview
1–14
Sep 5Chapter 2-Protein Structure and Function
Chapter 3-Enzymes: Structure and Function
15–41Chapter 1 HW DUE
Sep 12Chapter 4-Receptors: Structure and Function
Chapter 5-Receptors and Signal Transduction
42–72Chapter 2,3 HW DUE
Sep 19Chapter 6-Nucleic Acids: Structure and Function
Case Studies-
73–85Chapter 4,5 HW DUE
Sep 26Exam 1: Chapters 1–6Chapter 6 HW DUE
Oct 3Chapter 7-Enzymes as Drug Targets
Chapter 8-Receptors as Drug Targets
87–119
Oct 10Chapter 8-Receptors as Drug Targets
Chapter 9-Nucleic Acids as Drug Targets
Chapter 7,8 HW DUE
Oct 17Chapter 9-Nucleic Acids as Drug Targets
Individual Project Discussion
Class Start at 10 am
Chapter 9 HW DUE
Oct 24Chapter 10-Miscellaneous Drug TargetsChapter 10 HW DUE
Oct 31Case Studies-Presentations
Nov 7Chapter 11-Pharmacokinetics and Related Topics152–181Chapter 11 HW DUE
Nov 14Chapter 12-Drug Discovery: Finding a Lead
Chapter 13-Drug Design: Optimizing Target Interactions
185–240Chapter 12, 13 HW DUE
Nov 21Chapter 14-Drug Design: Optimizing Access to the Target
Chapter 15-Getting the Drug to Market
241–280Chapter 14,15 HW DUE
Nov 28–––––––––Thanksgiving Holiday—No Class–––––––––
Dec 5Selected Topics in Medicinal Chemistry-Student Presentations
Dec 11 (Wed)Selected Topics in Medicinal Chemistry-Student Presentations

Instructor's policies on late assignments and/or makeup work

Late Work

Late work (excluding in-class quizzes and exams) is accepted for up to 6 days after the original due date upon agreement to a 30% deduction. If you don’t agree, then please don’t ask me to accept your late work. Assignments more than 7 days late will not be accepted and receive a score of zero.

Extra Credit

There isn’t any so don’t ask. I understand people learn and express understanding differently. If you are struggling, I may be able to assist and offer valuable advice, but you need to initiate contact and be willing to follow the suggestions. The later help is sought, the less effective it will be.

––I do not give individuals opportunities for points the entire class does not have––

Additional Late Work Clarification (from Class Rules)

Late work will be accepted for up to 6 days after the stated due date only if you agree to a loss of 30% of the original value for the assignment. If you don’t agree, then don’t ask me to accept it. Late work includes the following causes: “It was done, but I left it ____ (fill in the blank)”; “I didn’t realize it was due”; “I wasn’t here when you announced the due date”.

Attendance Policy

Attendance

It is highly suggested students make all efforts possible to attend lectures. Consequences of being absent from class may include missing: information presented, application problems/quizzes, alteration of assignment due dates, etc. Inform me ASAP upon missing class due to unforeseen events.

Missing Class (from Class Rules)

Missing class is a choice that you make. The consequences of this include missing information presented, unannounced quizzes, alterations of due dates for assignments, etc. Accepted excuses for missing class include University excused absences and medical emergencies. I need proof and should be made aware of these in advance or ASAP. Unacceptable excuses include your wedding, being locked out of your house, sleeping in, and any other creative excuse that doesn’t fit the above, accepted excuses.

Course Fees

[3 Credits | $43.50 fee]

Prerequisites and Repeatability

Prerequisite(s): Instructor permission

Repeatable for Add’l Credit? Yes - Total Times: 1

Focus on the major concepts. Continually ask why and strive to understand. Take time to think about the reading. Learn to schedule your time effectively. Adhere to the reading schedule. DO NOT wait until the chapter/section is complete to start homework; complete problems as you read and in conjunction with the discussion of material in the lecture. If you plan now (meaning day one) to spend time studying each day the material will be much easier to understand, leading to success on exams and in class. I can’t do this for you.

Chemistry tutors are available. For more information see: /

––Remember: Lack of planning on your part does not constitute an emergency on my part––

Experience mandates the following rules to be established.

These rules may be altered or added to at any time with applicable disclosure.

You signed up for this course and in doing so agree to the terms found in this syllabus. These include agreeing that it is your responsibility to: attend class; take tests on the assigned day, and turn in assignments when due. You also agree it is not my responsibility to alter the outlined requirements, expectations, or due dates for this course.

Electronic devices not related to the learning environment are not allowed. Cell phones, smartwatches, etc. are not to be used in class as a calculator. Buy a proper calculator. I am not going to babysit individuals. If you bring a phone out I will assume you are not being challenged and will provide a quiz to the class to better engage you. Further implications include loss of grade curving and bonus projects, and in extreme cases loss of the object, grade drop, or dismissal from class.

Disruptive behavior cannot be tolerated, and participants will be asked to leave; this includes but is not limited to: texting, talking, sleeping, studying for other courses, arriving late, ringing phones, playing games, distracting activities on a computer, wearing head/earphones, or picking your nose. Don’t embarrass me by making me call you out!

Cheating will not be tolerated. See the academic integrity section.

Late work will be accepted for up to 6 days after the stated due date only if you agree to a loss of 30% of the original value for the assignment. If you don’t agree, then don’t ask me to accept it. Late work includes the following causes: “It was done, but I left it ____ (fill in the blank)”; “I didn’t realize it was due”; “I wasn’t here when you announced the due date”.

Personal matters that may interfere with you completing this course or an assignment are just that, personal. While I’ll try to be empathetic and understanding you need to understand that everybody has challenges. If you know that challenges will arrive during this course, like a birth, wedding, vacation, or are currently experiencing multiple challenges you are encouraged now not to take this course.

Stapling work is your responsibility; however, I am willing to perform this task for you for 2 points per staple. Also, if you need help organizing the pages of an assignment in the required order, I will do this for 2 points.

8½ x 11 paper is the standard in the United States. For the good of the country and your grade, assignments are to be turned in on this paper. It may have lines, but no frayed edges. I am willing to pull off the annoying ‘chads’ from spiral-bound notebooks for 2 points.

Translation services for those who don’t see the need to write clearly or organize their work in such a manner to make it clear what is being done are charged at a rate of up to 20% of the assignment's total value. (10% legibility, 10% organization)

Complete sentences are the only way to answer a question. To encourage complete sentences a charge of 1 point per infraction will be assessed for lack of a complete sentence or phrase.

Email etiquette, while not a rule, has an academic impact. Failure to use proper grammar, spelling, punctuation, and vocabulary reflects poorly on your academic abilities. Don’t send me an email that you wouldn’t send as part of a professional school application or employment application, SRSLY AFAIK, LOL.

University students are held to a higher standard. The above rules may seem childish or unfair, but as initially stated experience mandates such measures. Ideally, these rules protect those who are here to get a higher education from those who have yet to realize they are at a university. If you don’t agree to abide by these rules, you have a couple of options; take the class from a different instructor, suffer the outlined consequences, call me bad names, give me a bad evaluation, or change majors. If you agree to these rules, I promise a better education and skills that will be invaluable in all aspects of life.

ADA Statement

Students with medical, psychological, learning, or other disabilities desiring academic adjustments, accommodations, or auxiliary aids will need to contact the Disability Resource Center, located in Room 206F of the Sharwan Smith Center or by phone at (435) 865-8042. The Disability Resource Center determines eligibility for and authorizes the provision of services.

If your instructor requires attendance, you may need to seek an ADA accommodation to request an exception to this attendance policy. Please contact the Disability Resource Center to determine what, if any, ADA accommodations are reasonable and appropriate.

Academic Credit

According to the federal definition of a Carnegie credit hour: A credit hour of work is the equivalent of approximately 60 minutes of class time or independent study work. A minimum of 45 hours of work by each student is required for each unit of credit. Credit is earned only when course requirements are met. One (1) credit hour is equivalent to 15 contact hours of lecture, discussion, testing, evaluation, or seminar, as well as 30 hours of student homework. An equivalent amount of work is expected for laboratory work, internships, practica, studio, and other academic work leading to the awarding of credit hours. Credit granted for individual courses, labs, or studio classes ranges from 0.5 to 15 credit hours per semester.

Academic Freedom

SUU is operated for the common good of the greater community it serves. The common good depends upon the free search for truth and its free exposition. Academic Freedom is the right of faculty to study, discuss, investigate, teach, and publish. Academic Freedom is essential to these purposes and applies to both teaching and research.

Academic Freedom in the realm of teaching is fundamental for the protection of the rights of the faculty member and of you, the student, with respect to the free pursuit of learning and discovery. Faculty members possess the right to full freedom in the classroom in discussing their subjects. They may present any controversial material relevant to their courses and their intended learning outcomes, but they shall take care not to introduce into their teaching controversial materials which have no relation to the subject being taught or the intended learning outcomes for the course.

As such, students enrolled in any course at SUU may encounter topics, perspectives, and ideas that are unfamiliar or controversial, with the educational intent of providing a meaningful learning environment that fosters your growth and development. These parameters related to Academic Freedom are included in SUU Policy 6.6.

Academic Misconduct

Scholastic honesty is expected of all students. Dishonesty will not be tolerated and will be prosecuted to the fullest extent (see SUU Policy 6.33). You are expected to have read and understood the current SUU student conduct code (SUU Policy 11.2) regarding student responsibilities and rights, the intellectual property policy (SUU Policy 5.52), information about procedures, and what constitutes acceptable behavior.

Please Note: The use of websites or services that sell essays is a violation of these policies; likewise, the use of websites or services that provide answers to assignments, quizzes, or tests is also a violation of these policies. Regarding the use of Generative Artificial Intelligence (AI), you should check with your individual course instructor.

Emergency Management Statement

In case of an emergency, the University's Emergency Notification System (ENS) will be activated. Students are encouraged to maintain updated contact information using the link on the homepage of the mySUU portal. In addition, students are encouraged to familiarize themselves with the Emergency Response Protocols posted in each classroom. Detailed information about the University's emergency management plan can be found at https://www.suu.edu/emergency.

HEOA Compliance Statement

For a full set of Higher Education Opportunity Act (HEOA) compliance statements, please visit https://www.suu.edu/heoa. The sharing of copyrighted material through peer-to-peer (P2P) file sharing, except as provided under U.S. copyright law, is prohibited by law; additional information can be found at https://my.suu.edu/help/article/1096/heoa-compliance-plan.

You are also expected to comply with policies regarding intellectual property (SUU Policy 5.52) and copyright (SUU Policy 5.54).

Mandatory Reporting

University policy (SUU Policy 5.60) requires instructors to report disclosures received from students that indicate they have been subjected to sexual misconduct/harassment. The University defines sexual harassment consistent with Federal Regulations (34 C.F.R. Part 106, Subpart D) to include quid pro quo, hostile environment harassment, sexual assault, dating violence, domestic violence, and stalking. When students communicate this information to an instructor in-person, by email, or within writing assignments, the instructor will report that to the Title IX Coordinator to ensure students receive support from the Title IX Office. A reporting form is available at https://cm.maxient.com/reportingform.php?SouthernUtahUniv

Non-Discrimination Statement

SUU is committed to fostering an inclusive community of lifelong learners and believes our university's encompassing of different views, beliefs, and identities makes us stronger, more innovative, and better prepared for the global society.

SUU does not discriminate on the basis of race, religion, color, national origin, citizenship, sex (including sex discrimination and sexual harassment), sexual orientation, gender identity, age, ancestry, disability status, pregnancy, pregnancy-related conditions, genetic information, military status, veteran status, or other bases protected by applicable law in employment, treatment, admission, access to educational programs and activities, or other University benefits or services.

SUU strives to cultivate a campus environment that encourages freedom of expression from diverse viewpoints. We encourage all to dialogue within a spirit of respect, civility, and decency.

For additional information on non-discrimination, please see SUU Policy 5.27 and/or visit https://www.suu.edu/nondiscrimination.

Pregnancy

Students who are or become pregnant during this course may receive reasonable modifications to facilitate continued access and participation in the course. Pregnancy and related conditions are broadly defined to include pregnancy, childbirth, termination of pregnancy, lactation, related medical conditions, and recovery. To obtain reasonable modifications, please make a request to title9@suu.edu. To learn more visit: https://www.suu.edu/titleix/pregnancy.html.

Disclaimer Statement

Information contained in this syllabus, other than the grading, late assignments, makeup work, and attendance policies, may be subject to change with advance notice, as deemed appropriate by the instructor.